1,1-diMethylethyl ester (9CI)

1,1-diMethylethyl ester (9CI) - Names and Identifiers

Name	tert-Butyl (5-methylpyrazin-2-yl)carbamate
Synonyms	pyrazin-2-yL 2-Boc-Amino-5-methylpyrazine 1,1-diMethylethyl ester (9CI) 2-N-Boc-aMino-5-Methylpyrazin N-Boc-2-amino-5-methylpyrazine tert-Butyl (5-methylpyrazin-2-yl)carbamate tert-butyl N-(5-Methylpyrazin-2-yl)carbaMate CarbaMic acid,N-(5-Methyl-2-pyrazinyl)-, 1,1-diMethylethyl ester Carbamic acid, N-(5-methyl-2-pyrazinyl)-, 1,1-dimethylethyl ester Carbamic acid, (5-methylpyrazinyl)-, 1,1-dimethylethyl ester (9CI)
CAS	369638-68-6
EINECS	200-589-5
InChI	InChI=1/C10H15N3O2/c1-7-5-12-8(6-11-7)13-9(14)15-10(2,3)4/h5-6H,1-4H3,(H,12,13,14)

1,1-diMethylethyl ester (9CI) - Physico-chemical Properties

Molecular Formula	C10H15N3O2
Molar Mass	209.24
Density	1.154±0.06 g/cm3(Predicted)
Boling Point	268.8±40.0 °C(Predicted)
Flash Point	116.344°C
Vapor Presure	0.008mmHg at 25°C
pKa	11.63±0.70(Predicted)
Storage Condition	Sealed in dry,Store in freezer, under -20°C
Refractive Index	1.543

1,1-diMethylethyl ester (9CI) - Introduction

tert-Butyl (5-methylpyrazin-2-yl)carbamate, the chemical name is tert-Butyl (5-methylpyrazin-2-yl)carbamate, is an organic compound. The following is its nature, use, preparation and safety information:

Nature:
-Appearance: tert-Butyl (5-methylpyrazin-2-yl) is carbamate a white to pale yellow powdery solid.
-Melting point: about 90-100 degrees Celsius.
-Solubility: Soluble in some organic solvents, such as methanol, ethanol and dichloromethane.

Use:
tert-Butyl (5-methylpyrazin-2-yl)carbamate is commonly used as an intermediate in organic synthesis. It can be used to synthesize various active organic compounds, such as pesticides, drugs, dyes, etc.

Preparation Method:
tert-Butyl (5-methylpyrazin-2-yl)carbamate can be prepared by the following steps:
1. First, 2-amino -5-methyl pyrazine and tert-butyl chloroformate are reacted to generate tert-Butyl (5-methylpyrazin-2-yl)carbamate.
2. The reaction can be carried out at room temperature, and the reaction time is generally several hours.
3. After completion of the reaction, the product can be purified by crystallization or column chromatography.

Safety Information:
- tert-Butyl (5-methylpyrazin-2-yl)carbamate has high safety, but protective measures still need to be paid attention.
-Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
-Avoid direct contact with skin, eyes and respiratory tract.
-storage should be placed in a dry, well-ventilated place, away from fire and oxidant.
-When dealing with waste from tert-Butyl (5-methylpyrazin-2-yl)carbamate, it should be properly disposed of in accordance with local regulations.

Last Update：2024-04-09 21:01:54